.MacFeeters Hamilton Neuro-Oncology Plan, Little Princess Margaret Cancer Centre, College Health Network as well as Educational Institution of Toronto, Toronto, Ontario, CanadaJustin Z. Wang, u00c2 Vikas Patil, u00c2 Alexander P. Landry, u00c2 Chloe Gui, u00c2 Andrew Ajisebutu, u00c2 Jeff Liu, u00c2 Rebeca Yakubov, u00c2 Ramneet Kaloti, u00c2 Farshad Nassiriu00c2 & u00c2 Gelareh ZadehDivision of Neurosurgery, Division of Surgery, University of Toronto, Toronto, Ontario, CanadaJustin Z. Wang, u00c2 Alexander P. Landry, u00c2 Chloe Gui, u00c2 Farshad Nassiriu00c2 & u00c2 Gelareh ZadehPrincess Margaret Cancer Cells Centre, Educational Institution Health Network, Toronto, Ontario, CanadaJustin Z. Wang, u00c2 Vikas Patil, u00c2 Alexander P. Landry, u00c2 Chloe Gui, u00c2 Andrew Ajisebutu, u00c2 Jeff Liu, u00c2 Rebeca Yakubov, u00c2 Ramneet Kaloti, u00c2 Farshad Nassiriu00c2 & u00c2 Gelareh ZadehDalla Lana University of Public Health, College of Toronto, Toronto, Ontario, CanadaOlli SaarelaNRG Oncology Statistics as well as Data Control Facility, Philly, PA, USAStephanie L. Pughu00c2 & u00c2 Minhee WonTemerty School of Medication, College of Toronto, Toronto, Ontario, CanadaZeel PatelNeurosurgery Specialists of Tulsa, Tulsa, OK, USAChristopher WilsonDepartment of Nerve Surgical Procedure, Keck Institution of Medication of the University of Southern The Golden State, Los Angeles, CA, USAAaron Cohen-GadolDepartment of Nerve Surgical Procedure, Indiana College Institution of Medicine, Indianapolis, IN, USAMohamed A. ZaazoueDepartment of Orthopedic Surgical Procedure, Washington University Institution of Medicine in St. Louis, St. Louis, MO, USAMohamed A. ZaazoueGerman Cancer Cells Range (DKTK), DKFZ Companion Internet Site Tu00c3 1/4 bingen, Tu00c3 1/4 bingen, GermanyGhazaleh TabatabaiCluster of Excellence (EXC 2180) u00e2 $ Photo Led and also Functionally Directed Growth Therapiesu00e2 $, Eberhard Karls University Tu00c3 1/4 bingen, Tu00c3 1/4 bingen, GermanyGhazaleh TabatabaiDepartment of Neurology and also Interdisciplinary Neuro-Oncology, Center for Neuro-Oncology, Comprehensive Cancer Facility, Hertie Institute for Scientific Human Brain Study, Eberhard Karls University Tu00c3 1/4 bingen, Tu00c3 1/4 bingen, GermanyGhazaleh Tabatabai, u00c2 Sylvia C. Kurzu00c2 & u00c2 Paul PasslackDepartment of Neurosurgery, Facility for Neuro-Oncology, Comprehensive Cancer Facility, Eberhard Karls University Tu00c3 1/4 bingen, Tu00c3 1/4 bingen, GermanyMarcos Tatagiba, u00c2 Felix Behling, u00c2 Mirjam Renovanz, u00c2 Jens Schittenhelmu00c2 & u00c2 Paul PasslackDepartment of Pathology, Educational Institution of San Francisco, San Francisco, CA, USADamian A. Almiron BonninHuman Biology Branch, Fred Hutchinson Cancer Cells Center, Seattle, WA, USAEric C. HollandDepartment of Human Being Oncology, Educational Institution of Wisconsin Hospitals as well as Clinics, Madison, WI, USATim J. KruserCentral Brain Growth Registry of the USA, Hinsdale, IL, USAJill S. Barnholtz-Sloanu00c2 & u00c2 Jill Barnholtz-SloanTrans Divisional Investigation Course (TDRP), Branch of Cancer Cells Epidemiology as well as Genes (DCEG), National Cancer Principle, Bethesda, MD, USAJill S. Barnholtz-Sloanu00c2 & u00c2 Jill Barnholtz-SloanCenter for Biomedical Informatics & Information Technology (CBIIT), National Cancer Institute, Bethesda, MD, USAJill S. Barnholtz-Sloanu00c2 & u00c2 Jill Barnholtz-SloanPiedmont Human Brain Lump Center, Piedmonth Medical Care Device, Atlanta Georgia, GA, USAAndrew E. Sloanu00c2 & u00c2 Andrew E. SloanDepartment of Pathology, Northwestern University, Evanston, IL, USACraig Horbinskiu00c2 & u00c2 Craig M. HorbinskiLou & Jean Malnati Human Brain Growth Institute at the Lurie Comprehensive Cancer Cells Center, Northwestern College, Evanston, IL, USACraig Horbinskiu00c2 & u00c2 Craig M. HorbinskiDepartment of Neurosurgery, Vanderbilt College Medical Center, Nashville, TN, USASilky Chotaiu00c2 & u00c2 Lola B. ChamblessDepartment of Laboratory Medicine and Pathobiology, Educational Institution of Toronto, Toronto, Ontario, CanadaAndrew GaoDivision of Neurosurgery, College of British Columbia, Vancouver, British Columbia, CanadaAlexander D. Rebchuku00c2 & u00c2 Serge MakarenkoDepartment of Pathology & Laboratory Medication, Professors of Medicine, University of British Columbia, Vancouver, British Columbia, CanadaStephen YipDepartment of Neuropathology, Institute of Pathology, Ruprecht-Karls-University Heidelberg, Heidelberg, GermanyFelix Sahm, u00c2 Felix Sahmu00c2 & u00c2 Andreas von DeimlingClinical Participation System Neuropathology, German Cancer Cells Proving Ground (DKFZ), Heidelberg, GermanyFelix SahmDepartment of Pathology, Leiden University Medical Facility, Leiden, The NetherlandsSybren L. N. MaasDepartment of Pathology, Erasmus MC Cancer Cells Institute, University Medical Center Rotterdam, Rotterdam, The NetherlandsSybren L. N. MaasRadiation Medication System, Princess Margaret Cancer Facility, Toronto, Ontario, CanadaDerek S. TsangRadiation Oncology, Utah Cancer Cells Specialists, Salt Lake Urban Area, UT, USAC. Leland RogersCenter for Cancer Investigation, National Cancer Cells Principle, Bethesda, MD, USAKenneth AldapeMiami Neuroscience Institute, Baptist Health, Miami, FL, USAMichael W. McDermottDepartment of Neurosurgery, Addenbrookeu00e2 $ s Hospital, Cambridge, UKThomas Santariusu00c2 & u00c2 Daniel M. FountainDepartment of Neurosurgery, University Hospitals Cleveland and Scenario Western Get University, Cleveland, OH, USAWarren SelmanDepartment of Pathology, College Hospitals Situation Medical Facility, Cleveland, OH, USAMarta CouceDepartment of Neurosurgery, Centro Hospitalar Universitu00c3 u00a1 rio S. Jou00c3 u20a4 o, Porto, PortugalBruno CarvalhoCenter for Neuro-Oncology, Dana-Farber/Brigham and Womenu00e2 $ s Cancer Facility, Boston Ma, MA, USAPatrick Y. WenDepartment of Neurosurgery, Battle Each Other College, Durham, NC, USAKyle M. WalshDepartment of Neurosurgery, Erasmus MC Cancer Cells Institute, Erasmus University Medical Facility, Rotterdam, The NetherlandsEelke M. BosDepartment of Neurosurgery, Brigham as well as Womenu00e2 $ s Hospital, Harvard Medical University, Boston, MA, USAWenya Linda BiDepartment of Radiology, Brigham and Womenu00e2 $ s Hospital, Dana-Farber Cancer Principle, Harvard Medical College, Boston Ma, MA, USARaymond Y. HuangDepartment of Neurology, Branch of Neuro-Oncology, Massachusetts General Hospital, Harvard Medical Institution, Boston, MA, USAPriscilla K. BrastianosDepartment of Radiation Oncology, Massachusetts General Hospital, Boston Ma, MA, USAHelen A. ShihDepartment of Neurology, Hermelin Brain Tumor Facility, Henry Ford Health, Detroit, MI, USATobias WalbertDepartment of Neurosurger, Hermelin Human Brain Tumor Center, Holly Ford Health And Wellness, Detroit, MI, USAIan Lee, u00c2 Ana Valeria Castro, u00c2 Houtan Noushmehru00c2 & u00c2 James M. SnyderDepartment of Pathology, Educational Institution of Texas Medical Branch, Galveston, TX, USAMichelle M. FelicellaDepartment of Neurosurgery, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, ItalyFrancesco Dimecou00c2 & u00c2 Andrea SaladinoNeuropathology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, ItalyBianca PolloDepartment of Neurosurgery, LMU Teaching Hospital, LMU Munich, Munich, GermanyChristian Schichoru00c2 & u00c2 Ju00c3 u00b6 rg-Christian TonnDepartment of Radiation Oncology, Charitu00c3 u00a9 u00e2 $ "Universitu00c3 $ tsmedizin Berlin, Corporate Member of Freie Universitu00c3 $ t Berlin and also Humboldt-Universitu00c3 $ t zu Berlin, Berlin, GermanyFelix EhretDepartment of Radiology, Mayo Medical Clinic, Rochester, MN, USATimothy J. KaufmannDepartment of Lab Medication and Pathology, Mayonnaise Facility, Rochester, MN, USADaniel H. Lachance, u00c2 Caterina Gianniniu00c2 & u00c2 Aditya RaghunathanDepartment of Oncology, Branch of Medical Oncology, Mayo Medical Clinic, Rochester, MN, USAEvanthia GalanisDepartments of Neuro-Oncology as well as Neurosurgery, Moffitt Cancer Facility, Tampa Florida, FL, USAMichael A. VogelbaumNeuropathology System, Surgical Neurology Division, National Institute of Nerve Disorders and Movement, National Institutes of Wellness, Bethesda, MD, USAPatrick J. CiminoDepartment of Nerve Surgery, Northwestern Educational Institution, Northwestern Medicine, Chicago, IL, USAMark YoungbloodDepartment of Pathology, NYU Langone Medical Facility, Nyc, NY, USAMatija SnuderlDepartment of Radiation Oncology, NYU Langone Wellness, Nyc College, Nyc, NY, USAErik P. SulmanDepartment of Neurosurgery, University of Oklahoma Wellness Sciences Facility, Oklahoma Urban Area, OK, USAIan F. DunnPeninsula Schools of Medication and Dentistry, Plymouth Educational Institution, Plymouth, UKC. Oliver HanemannDepartment of Neurosurgery, Royal College of Surgeons in Ireland, Dublin, IrelandMohsen JavadpourDepartment of Anatomical and also Cell Pathology, Chinese Educational Institution of Hong Kong, Shatin, Hong KongHo-Keung NgDepartment of Human Genes, College of The Golden State, Los Angeles, Los Angeles, CA, USAPaul C. BoutrosDepartment of Neurosurgery, College of The Golden State, Los Angeles, Los Angeles, USARichard G. EversonDepartment of Neurosurgery, Teaching Hospital of Larissa, University of Medicine, Educational Institution of Thessaly, Larissa, GreeceAlkiviadis Tzannisu00c2 & u00c2 Konstantinos N. FountasDepartment of Neurosurgery, College Medical Center Regensburg, Regensburg, GermanyNils Ole SchmidtDepartment of Surgery, Branch of Neurosurgery, College of Alberta, Edmonton, Alberta, CanadaKarolyn AuCenter of Neurosurgery, Team of General Neurosurgery, Educational Institution of Fragrance, Perfume, GermanyRoland GoldbrunnerDepartment of Neurology, Faculty of Medicine, University Hospital Fragrance, College of Cologne, Cologne, GermanyNorbert GalldiksLaboratory for Neurooncology and also Speculative Neurosurgery, Department of General Neurosurgery, Facility for Neurosurgery, Fragrance, GermanyMarco TimmerDepartment of Neurosurgery, Teaching Hospital of Copenhagen-Rigshospitalet, Copenhagen, DenmarkTiit Illimar MathiesenDepartment of Neurosurgery, Educational Institution Medical Center Hamburg-Eppendorf, Hamburg, GermanyManfred Westphal, u00c2 Katrin Lamszusu00c2 & u00c2 Franz L. RicklefsDepartment of Neurosurgery, Teaching Hospital Heidelberg, Heidelberg, GermanyChristel Herold-Mende, u00c2 Christine Jungku00c2 & u00c2 Gerhard JungwirthDepartment of Radiation Oncology, Heidelberg University Hospital, Heidelberg, GermanyMaximilian DengLeeds Institute of Medical Investigation at St. Jamesu00e2 $ s, Educational institution of Leeds, Leeds, UKSusan C. ShortDepartment of Neurosurgery, The Walton Facility NHS Base Trust, Liverpool, UKMichael D. JenkinsonInstitute of Neuropathology, Otto-Von-Guericke-University, Magdeburg, GermanyChristian MawrinDepartment of Neurosurgery, Manchester Centre for Clinical Neurosciences, Salford Royal Hospital NHS Foundation Trust, Salford, UKAbdurrahman I. Islimu00c2 & u00c2 Omar N. PathmanabanDepartment of Neurosurgery, Royal Melbourne Health Center, Melbourne, VIC, AustraliaKatharine J. Drummondu00c2 & u00c2 Andrew MorokoffDepartment of Radiation Oncology, College of California, San Francisco, San Francisco, CA, USADavid R. RaleighDepartment of Neurosurgery, Educational Institution of California, San Francisco, San Francisco, CA, USADavid R. Raleighu00c2 & u00c2 Nicholas A. ButowskiDepartment of Pathology, University of California, San Francisco, San Francisco, CA, USADavid R. Raleighu00c2 & u00c2 Arie PerrySchool of Pharmaceutical Sciences of Ribeiru00c3 u20a4 o, Preto College of Su00c3 u20a4 o Paulo, Su00c3 u20a4 o Paulo, BrazilTathiane M. MaltaDepartment of Pathology and Research Laboratory Medicine, University of Saskatchewan College of Medication, Saskatoon, Saskatchewan, CanadaViktor ZherebitskiyDivision of Neurosurgery, Royal University Hospital, University of Saskatchewan, Saskatoon, Saskatchewan, CanadaLuke HnennyUSC Pituitary Facility, USC Radiosurgery Facility, Keck School of Medicine of USC, Los Angeles, CA, USAGabriel ZadaDepartment of Neurosurgery, St. Barbara-Klinik Hamm-Heessen, Hamm, GermanyAntonio SantacroceNuclear Medication and Clinical Molecular Image Resolution, Division of Radiology, Eberhard Karls University of Tu00c3 1/4 bingen, Tu00c3 1/4 bingen, GermanyChristian la Fougu00c3 u00a8 reDepartment of Neurosurgery, Yale University of Medicine, New Sanctuary, CT, USAJennifer MoliternoDepartment of Neurosurgery, Tufts Medical Center, Boston Ma, MA, USAAlper DincerArthur and also Sonia Labatt Brain Tumor Analysis Facility, The Medical Facility for Sick Children, Toronto, Ontario, CanadaGelareh ZadehManuscript writing, figure preparation, basic statistical evaluation as well as basic bioinformatics were actually done through J.Z.W. Molecular classification, model property as well as bioinformatics sustain was actually provided through V.P., A.P.L. and J.L. TERT marketer sequencing was actually conducted by C.G. Duplicate number alternative analysis and referring to as were performed by A.P.L. Molecular analyte extraction, metrology and also sequencing were actually executed by J.Z.W., A.P.L., C.G., A.A. and Z.P. DKFZ methylation training class and also subclass determination was performed through R.Y. as well as R.K. using the publicly on call online tool made through F.S. RNA sequencing evaluation was actually conducted through V.P. as well as J.L. Biostatistical customer review was conducted through O.S. Scientific records from the NRG Oncology RTOG-0539 meningioma scenarios were actually delivered by S.L.P. as well as M.W. Professional meningioma samples as well as matching clinical information were offered through C.W., A.C.G., M.A.Z., G.T., M.T., F.B., D.A.A.B., E.C.H., J.B.S., A.E.S., C.H., S.C., L.B.C., A.R., S.M. and S.Y. Pathologic review was actually conducted through A.G. as well as K.A. Radiotherapy records of institutional retrospective meningioma cases were actually supplied by D.S.T. Research layout and also conception were carried out through J.Z.W, F.N. as well as G.Z. All authors joined document review as well as modifications in some capability.